My Current Longevity Stack

TL;DR

The speaker's longevity stack is deliberately conservative — creatine, vitamin D, magnesium monitoring, urolithin A, ketone esters, and cautious rapamycin experimentation.

Key Points

• 1.The core stack is intentionally minimal. Creatine and vitamin D form the foundation, with magnesium monitoring for those on medications like omeprazole that inhibit absorption, plus urolithin A given mounting data on mitochondrial health.
• 2.Rapamycin is considered interesting but risky. The speaker is exploring combining Norwegian 4x4 interval training with rapamycin pulsing to measure volumetric hippocampal changes, but warns any immunosuppressant use requires extreme caution.
• 3.Ketone esters and fasting target brain health. Given family history of Alzheimer's and Parkinson's, ketone esters are explored for cerebral vascular benefits; intermittent and 3–7 day fasting (including fast-mimicking diets per Dr. Dominic D'Agostino) are used to foster autophagy and mitophagy.
• 4.Ibogaine flood dosing is highlighted as a powerful 'reboot.' Under medical supervision with magnesium co-administration, ibogaine can eliminate opiate withdrawal symptoms and may reverse brain age per Nolan Williams' MRI research on veterans with traumatic brain injury.
• 5.Brain stimulation is flagged as the most exciting next frontier. Non-invasive and potentially invasive bioelectric medicine is seen as surpassing pills and IVs for both psychiatric treatment and performance enhancement, with outpatient procedures potentially lasting just one to two hours.